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The metabolic pathways promote the development of an immunosuppressive vascular microenvironment, thereby facilitating resistance to chemotherapy [41]
In addition, iron and glutamate interact, as iron is involved in the synthesis of glutamate by activating cytosolic aconitase enzyme [133] and glutamate can increase the total brain iron content by making it easier for iron to enter the cell through the upregulation of DMT1
Interestingly, asparagine was reported to be able to rescue cancer cells from glutamine deprivation-induced apoptosis 43
Glutathione precursor, N-acetyl-cysteine, improves mismatch negativity in schizophrenia patients
Dose, delivery, and concentration are fundamentally different
By incorporating into selenoproteins, selenocysteine has a profound effect in reducing inflammation and oxidative stress
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