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Drink 8 to 10 (8-ounce) cups (2 liters) of liquids daily, if you can

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Under the approved dosing schedule, patients will begin with a daily dose of 1.5mg before gradually increasing through 4mg and 9mg to a maintenance dose of 25mg, spending at least one month at each stage

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Indeed, eGFR values were greater in patients on tirzepatide compared to those on insulin glargine, with a mean eGFR decline rate of 1.4 ml/min/1.73 m 2 per year in tirzepatide users and a between-group difference in eGFR reduction of 2.2 ml/min/1.73 m 2 per year [49]