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RoB2 examines 5 domains to evaluate the risk of bias in each RCT, whereas ROBINS-I evaluates observational studies in 7 domains to determine the risk of bias as low, some, or high concern

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The prodrug micelles loaded with V-9302 improved the bioavailability of V-9302 and demonstrated excellent anti-tumor activity by synergistically targeting two metabolic pathways (Luo et al., 2020)

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These findings have important clinical ramifications with the possibility of targeting ferroptosis pathway in GPX4-overexpressing thyroid cancers