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As key cellular components of the TME, CAFs display a heterogeneous makeup originating from diverse sources, including local fibroblasts and mesenchymal stem cells [113]
However, studies were not properly conducted in many clinics, and except for top centers 41 did not show significant differences between treatment groups
1 Introduction In recent years, the global incidence and mortality rates of cancer have been on the rise, making it a major cause of death worldwide (1)
Inflammatory Pathways: Research in laboratory settings has examined interactions with inflammatory signaling
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