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GSH seems to be a safe dietary supplement, likely because it is poorly transported and rapidly digested by peptidases

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Ahmadieh H, Azar ST

[1] The FDA granted the approval of Endari to Emmaus Medical Inc

It contains a number of ingredients that are occlusives and are good to moisturize dry and very dry skin such as Ethylhexyl Palmitate, Dimethicone, and Cetyl Stearyl Alcohol

A 2023 systematic review and meta-analysis of randomized controlled trials found that oral collagen supplementation was associated with significant improvements in skin hydration and elasticity compared with placebo