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Insert the needle at a 45- to 90-degree angle in a quick, smooth motion

Prevents Hyperpigmentation B12 deficiency can sometimes lead to hyperpigmentation or dark spots on the skin

(PubMed) Potter K, Hankey GJ, Green DJ, Eikelboom J, Jamrozik K, Arnolda LF

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3.4 Changes in serum homocysteine by supplementation route and dosage Analysis of 10 comparisons showed that vitamin B12 supplementation was associated with a mean reduction of 35.8% in serum homocysteine concentrations (Supplementary Table S5)