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For example, as fingolimod traps lymphocytes in the lymph nodes,Reference Antel 116 efficacy of subsequent agents that target circulating lymphocytes such as alemtuzumabReference Hu, Turner and Shields 117 may be compromised

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Cell culture Human embryonic kidney cells (HEK293T, ATCC: CRL-11268), human cervical adenocarcinoma cells (HeLa, ATCC: CCL-2), Chinese hamster ovary cells (CHO-K1, ATCC: CCL-61), human telomerase-immortalized mesenchymal stem cells (hMSC-TERT), baby hamster kidney cells (BHK-21, ATCC: CCL-10) were cultured in Dulbeccos modified Eagles medium (DMEM

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