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Clinically, this results in increased blood pressure and heart rate due to unopposed sympathetic stimulation
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Specific enzymes, MTR, methionine synthase reductase, and MTHFR, can express polymorphisms that result in elevated homocysteinemia, a risk factor for having a child with DS [106]
The putative pathophysiological mechanisms of the association between elevated GGT activity and cardiometabolic risk have recently been reviewed [66]
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