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If NAION develops, the AOA recommends immediate discontinuation of the drug and coordination of care among all providers managing the patient's health

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PRIMM study 38,39 : patients with advanced melanoma who were treated with immune-checkpoint blockade were prospectively included between August 2015 and January 2020 in the UK studies Predicting Response to Immunotherapy for Melanona with Gut Microbiome and Metabolomics (PRIMMUK) and the Netherlands studies (PRIMMNL, made up of eligible patients from the COLIPI, POINTING and OncoLifeS studies)

The liver is the bodys main detox organ, and glutathione is essential for breaking down harmful substances such as heavy metals, pollutants, and even the damage caused by acetaminophen overdoses