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M., Catalani, V., Martinotti, G., Sensi, S

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The very steep dose gradients that confer brachytherapy its tumoricidal advantage also pose a double-edged risk: minimal misalignment or anatomical variation can result in unintended irradiation of surrounding healthy tissue, leading to acute and late toxicities [101, 102]

These reactions produce degradation products that reduce potency and, in some cases, may increase immunogenicity

Contrary to popular belief, they dont just affect weight and blood sugar