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The depletion of NCOA4 or autophagy-related (ATG, such as ATG3, ATG5, ATG7, and ATG13) can impede ferritin degradation, resulting in the buildup of iron and lipid peroxidation, ultimately leading to ferroptosis (Mancias et al., 2014)

A 1-way ANOVA was used to analyze differences between 3 or more treatment groups using GraphPad Prism, version 4.0 (GraphPad Software)

Developed in collaboration with argenx, the study shows how HypoSkin can serve as a human-based New Approach Methodology (NAM) for early local tolerance and formulation safety screening

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This helps reduce chronic inflammation and may benefit inflammatory skin conditions, including psoriasis and eczema