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A misfolded or partially unfolded protein exposes hydrophobic surface, and that surface nucleates further aggregation

Research designs may include metabolic panels and body-composition proxy markers, depending on the study system and endpoints

Materials and Methods: A case-control study was conducted with 45 women with unexplained RPL (sampled during early pregnancy) and 45 healthy pregnant controls

Male patients, conversely, showed more pronounced peroxisome dysfunction and severe mitochondrial lipid oxidative damage

If that pathway is substrate-limited, fat accumulates in hepatocytes even as total body weight drops

Health implications of high dietary omega-6 polyunsaturated fatty acids