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Therefore, only rats that were unresponsive lost their righting reflex and whose pupils were dilated during ischemia were selected to evaluate completed cerebral ischemia, as recommended by Pulsinelli (Pulsinelli et al

NAC has superior oral bioavailability because it is absorbed as a single amino acid derivative rather than a tripeptide requiring intact absorption

Physiology 14, 1081186

In effect, the synthetic peptide predicted and prompted the discovery of a natural hormone