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In a combined multiple ascending dose (MAD) and Phase 2a study in people with type 2 diabetes over 41 days, the safety of cotadutide was confirmed (83)
A TrustCare primary care physician can review your overall health, discuss your goals, go over your medical history, and help you understand whether GLP-1 medications may be worth exploring along with any other options that may be a fit for your situation
American Diabetes Association 79th Scientific Sessions
Furthermore, exogenous GLP-1 can protect the intestine from oxidative damage by inhibiting neutrophil infiltration, and can reduce inflammatory mediators that induce LPO production, regulate intestinal homeostasis through local effects and restore intestinal integrity, thereby reducing bacterial translocation caused by intestinal barrier dysfunction (128)
Elashoff M, Matveyenko AV, Gier B et al
