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The synthetic GLP-1 receptor agonists mimic this endogenous hormone but are modified to resist rapid enzymatic breakdown by dipeptidyl peptidase-4 (DPP-4), thereby extending their duration of action
That does not mean retatrutide is available as an approved prescription weight-loss medication
Folate should be supplemented with it, particularly to help prevent colorectal cancer, which this drug otherwise promotes (Patel 2009
N.SchwartzM
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Nonetheless, investigators from the Canadian Network for Observational Drug Effect Studies (CNODES) reported contradictory results
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