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It is a theoretical concern based on mechanism, not an observed outcome
Neuropathic Pain and Tingling: By keeping the transsulfuration pathway open and clearing toxic homocysteine, P-5-P and NAC help protect peripheral nerves from vascular damage and oxidative degradation, which may reduce nerve pain and neuropathy
1), while the sugar moiety, through its hydroxyl groups, is close to the main chain carbonyls of G323 and R322 in one conformation and with the analogous groups of G437 and Q440 occupying the hydrophilic portion of subpocket A in the other conformation
10.1080/13510002.2021.1952819 Redox Rep
The oxidation of roGFP2 was investigated by mixing 2 M of reduced roGFP2 in syringe 1 with variable concentrations of glutathionylated or diamide-oxidized PfGrx in syringe 2
Others receive it as a quick stand-alone infusion
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