Semaglutide (Wegovy) is a GLP-1 receptor agonist
The problem is that translation from rodent models to human outcomes is notoriously unreliable, and we've been burned by promising animal data that didn't pan out in humans more times than anyone wants to count
G., Steinecker-Frohnwieser, B., Mobasheri, A., Bernotiene, E., Zaucke, F., et al
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Clinical studies suggest collagen supplementation may help: reduce knee osteoarthritis pain improve joint function support tendon rehabilitation when combined with exercise Examples of Osteoarthritis studies: Examples of Tendon studies: Unlike injectable peptides, collagen supplements function as nutritional support, not pharmacologic signaling molecules
GLP-1 receptor activation slows gastric emptying, increases satiety, and improves glucose-dependent insulin secretion