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In the highest-dose group studied (12 mg once weekly), mean weight loss approached 17.5% of body weight over 24 weeks

However, no human cases of medullary thyroid cancer have been causally linked to GLP-1 use in clinical trials or post-market surveillance

When that same excess fat is driving sleep apnea, joint pain, prediabetes, or PCOS (now called PMOS), it becomes clinical obesity, a disease causing real harm

Its particularly notable given that sales in all other markets continued to increase up 9% in the U.S., 17% in Europe and Canada, and 8% for the rest of the Asia-Pacific region

Only work with providers that require a licensed clinician to review your health history, prescribe treatment, and stay available for follow-ups

Current research suggests that visceral fat reductions achieved during treatment may not be fully maintained after discontinuation