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Here, we investigated the effects of maternal L-Carnitine supplementation on brain markers of oxidative stress, autophagy, mitophagy and mitochondrial energy producing oxidative phosphorylation (OXPHOS) complexes in SE offspring

Cystathionine -synthase: structure, function, regulation, and location of homocystinuria-causing mutations

Weinheimer EM, Sands LP, Campbell WW

5.4 GLP-1s anti-apoptotic effects GLP-1 RAs exhibit strong anti-apoptotic effects by activating the PI3K/Akt pathway, which promotes cell survival by inhibiting pro-apoptotic factors such as Bax and caspase-3, while upregulating anti-apoptotic proteins like Bcl-2 (104106)

CHX restored mTORC1 signaling and relieved the ISR under cystine starvation (Fig

5a, b and Supplementary Fig