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Many patients report feeling more energetic and active after completing their prescribed course
Everything here comes from published preclinical research
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Gastrointestinal effects: the main titration bottleneck Nausea, diarrhea, constipation, and vomiting run around 40 to 44% overall, dose-dependent in how many people report them but mild-dominant in severity: severe events stay at or below about 1.7% in any category even at the top dose. In the obesity program the by-dose rates run nausea 25/29/28%, diarrhea 19/21/23%, and vomiting 8/11/13% at 5/10/15 mg. They concentrate during escalation and ease with time on a held dose
The limited human data available has not shown significant safety concerns, but long-term human safety data is still being established
Patients often finish NAD+ treatment reporting positive effects (such as increased energy or mental clarity) with few downsides aside from the transient discomforts noted above
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