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Retatrutide and Mounjaro both come from Eli Lilly, both target metabolic hormones, and both produce significant weight loss in clinical trials
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Chatterjee DJ, Khutoryansky N, Zdravkovic M, Sprenger CR, Litwin JS: Absence of QTc prolongation in a thorough QT study with subcutaneous liraglutide, a once-daily human GLP-1 analog for treatment of type 2 diabetes
Important safety considerations include boxed warnings for thyroid C-cell tumors (based on animal studies), and cautions regarding pancreatitis and gallbladder disease
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