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PCPs adjust dose, pause treatment, or discontinue based on clinical response and tolerability

Semaglutide, the active ingredient in Ozempic and Wegovy, is a modified version of human GLP-1

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As a result, there is ongoing interest in exploring novel therapies that target the underlying metabolic and inflammatory pathways involved in the disease

Long-Acting strategies for GLP-1 RAs, source: Designing a Dual GLP-1R/GIPR Agonist from Tirzepatide: Comparing Residues Between Tirzepatide, GLP-1, and GIP, Drug Design, Development and Therapy, Oral Formulation The only available oral GLP-1RA is semaglutide (Rybelsus, Novo Nordisk)

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