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Elevated TMAO levels have been linked to a number of diseases, including cardiovascular and neurological disorders, renal disease, metabolic syndrome, obesity, type 2 diabetes (T2D), non-alcoholic fatty liver disease (NAFLD), cancer, and severe COVID-19

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Using a statistical modeling method designed to detect meaningful shifts in trends over time, researchers confirmed that semaglutide-related calls were growing at an additional 9.9% per quarter after the approval, far outpacing the modest growth seen among other drugs in the same class