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The decline in ferroptosis is brought about by increasing intracellular glutathione levels and inducing sirtuin-1, both of which strengthen glutathione-dependent glutathione peroxidase 4 [101]

Functional Effects of M PRO in Transfected Cells are Consistent With GPX1 Knockdown As detailed above, the original 2003 SCoV M pro has essentially identical substrate sequence specificity as that of SCoV2

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Our findings further suggested that TECs ferroptosis contributes to renal fibrosis and may exacerbate its progression

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