Considering the above results, our study was conducted using only clinical samples, without in vivo or in vitro validation
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This means that while the results demonstrate safety in a healthy population with low psychiatric risk, they do not directly prove safety in the vulnerable populations we are most concerned about [56,66]
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When glutathione availability declines, GPX4 activity falters, permitting unchecked lipid peroxidation, cardiomyocyte loss, and progression toward heart failure (19)