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Two independent experiments using 68 mice each (14 mice per group in total) from different litters were conducted
5-Amino-1MQ: inhibits NNMT
Because SAM is also required for many other methylation reactions, including gene-expression regulation, high NNMT activity draws heavily on SAM and is associated in studies with reduced NAD, a coenzyme central to cellular energy production
About this article Cite this article Lingaraj, J., Prabhu Shankar, D., Parameswaran, A
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