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5d) outlined metabolic pathways associated with some polar basic amino acids, such as lysine and CEL, secondary amides and other acid compounds, like aspartic acid derivatives and glutamic acid (Fig

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1 Introduction Ulcerative colitis (UC) is an idiopathic chronic inflammatory bowel disease (IBD) characterized by mucosal inflammation, which starts in the rectum and generally extends continuously to proximal segments of the entire colon ( Emerging research has recently revealed that mitochondrial dysfunction is implicated as a key factor in UC pathogenesis ( In our study, the most comprehensive colonic mucosal tissue transcriptomic data by integrating the publicly available UC transcriptome datasets to date were utilized to explore the mechanisms underlying mitochondrial action in UC through comprehensive bioinformatics analysis

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