A physician investigating unexplained hypercobalaminemia will typically order some combination of the following: Complete blood count (CBC) with differential to check for abnormal red blood cell, white blood cell, or platelet counts Liver function tests (ALT, AST, ALP, bilirubin, albumin) to assess liver health Kidney function tests (creatinine, BUN, estimated GFR) to evaluate renal clearance Peripheral blood smear if a myeloproliferative disorder is suspected Abdominal imaging (ultrasound or CT) if liver or abdominal pathology is a concern Cancer-specific markers or screenings if clinical suspicion warrants them The NIH Office of Dietary Supplements fact sheet notes that observational data from a Danish registry analysis of 757,185 people found the adjusted 1-year cancer risk was 1.74 to 4.72 times higher among those with B12 above 813 pg/mL compared to those in the normal range of 203 to 813 pg/mL

Reconstitution and Laboratory Handling HCG 5000IU must be reconstituted prior to laboratory use using bacteriostatic sterile water for injection, or another appropriate solvent which is valid in the lab following institutional procedures and best science practice
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Subsequent studies and patents from the same group of researchers showed that a 15 amino acid peptide derived from the N-terminus of BPC, now known as BPC 157, has many of the same effects as the entire protein