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others get sick after a sip

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[1] Renal function should be monitored if significant gastrointestinal symptoms or dehydration occur

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The XGBoost algorithm per se is not intended to be used in routine clinical work but was employed here to identify continuous baseline variables that predict the change in HbA1c and which can easily be evaluated by clinicians to provide a better overall assessment of the likely treatment response (such that for example a patient with high BMI or low insulin secretion will likely have a more pronounced response to a particular drug) in conjunction with other clinical data and the general patient context