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Mitochondrial dysfunction and -Synuclein synaptic pathology in parkinson's disease: who's on first

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It typically takes 8 to 12 weeks for the medication to reach its full effect

It directly stimulates pro-opiomelanocortin/cocaine-and-amphetamine-regulated transcript (POMC/CART) neurons and indirectly inhibits neuropeptide-Y/agouti-related protein (NPY/AgRP) neurons through GABA neurotransmission, reducing appetite and promoting weight loss [40]

N.et al (2019)