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European Journal of Internal Medicine

2017) and the upregulation of growth hormone (receptor) (Chang et al

It was originally developed as a potential treatment for obesity by researchers at Monash University

This aligns with the findings that activation of the PTEN-PI3K-mTORC1 pathway in prostate cancer leads to metabolic alterations in polyamine synthesis and decarboxylated S-adenosylmethionine (dcSAM) production, further underscoring the potential of metabolic markers in cancer detection and evaluation [37]