Some people notice mild soreness at the injection site, which typically resolves within a day
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The recommended injection site is the abdomen, in the soft tissue lateral to the navel
After that it slowly disappeared because it became more and more difficult to obtain radioactive B12 suitable for human use, and at the same time less and less acceptable to use radioactive B12 in a diagnostic test
Because oral supplements are absorbed less effectively, you need to take them far more frequently than you would need an injection