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Data from randomized controlled trials suggest that withdrawing either glucagon-like peptide-1 (GLP-1) receptor agonists or dual gastric inhibitory polypeptide (GIP)/GLP-1 receptor agonists leads to a substantial regain of lost weight

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Dual- and triple-receptor agonists also offer the potential for the treatment of obesity (6976)

All approved GLP-1 medications require subcutaneous injection or oral administration (Rybelsus), and patients should avoid purchasing unapproved patches marketed online