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A small study found that men who consumed one gram of yerba mate three times daily improved the rate of strength recovery following eccentric exercise

This is a concern that applies to all significant weight loss interventions, not just tirzepatide, but it becomes more relevant as the magnitude of weight loss increases

Sci China-Life Sci (2016) 59(1):3843

Always consult your healthcare team before making medication changes

Inhibition of growth of prostatic cancer cell lines by peptide analogues of insulin-like growth factor 1

Although these agents produce substantial and sustained weight reduction, emerging clinical observations suggest that chronic therapy may be accompanied by changes in lean mass trajectory, reduced protein intake, and micronutrient insufficiency