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[3] [4] Secretion [edit source] GLP-1 is packaged in secretory granules and secreted into the hepatic portal system by the intestinal L-cells located primarily in the distal ileum and colon, but also found in the jejunum and duodenum

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Como medida de precaucin, las guas actuales recomiendan suspender los medicamentos GLP-1 al menos uno o dos meses antes de intentar la concepcin, ya sea de manera natural o mediante un tratamiento de fertilidad