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It demonstrated a 23% relative reduction in MACEs with semaglutide compared to placebo

Long-acting glucagon-like peptide-1 receptor agonists suppress voluntary alcohol intake in male wistar rats

Pietrzik, K

Consequently, once-daily subcutaneous administration of liraglutide 3.0 mg was developed for the treatment of obesity [21] and once-weekly subcutaneous administration of semaglutide 2.4 mg is currently being investigated in phase III trials for this indication [22]

These reports should be interpreted as hypothesis-generating rather than clinically confirmed adverse-effect estimates

The Result: In the Chinese trial, patients lost significantly more weightup to 19.9%compared to standard GLP-1s