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The Evidence Multiple large cardiovascular outcome trials have demonstrated GLP-1 medications reduce heart attacks, strokes, and cardiovascular death: SUSTAIN-6 (semaglutide): 26% reduction in major adverse cardiovascular events (MACE) in patients with Type 2 diabetes and high cardiovascular risk

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Michigans telehealth parity law (PA 174 of 2020) requires insurers to cover telehealth services for covered benefits at parity with in-person services

Eli Lilly's own public statements have been measured

Both medications target more than one metabolic receptor, but retatrutide activates an additional pathway that may enhance fullness and metabolic signaling