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Possible effects include: Loose or excess skin Fatigue Hair thinning Muscle loss (if not strength training) Gallbladder issues with rapid loss Nutrient deficiencies if diet is poor Most risks are reduced with gradual weight loss, adequate protein, strength training, and medical supervision

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This distinct distribution suggests that the organs primarily involved in metabolic and reproductive functions may exhibit varying capacities for the uptake or retention of IGF-1 LR3 in contrast to IGF-I

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