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It plays a pivotal role in glucose metabolism and appetite regulation through multiple mechanisms: Enhances insulin secretion: GLP-1 stimulates pancreatic -cells to release insulin in a glucose-dependent manner Suppresses glucagon: Reduces hepatic glucose production Delays gastric emptying: Creates prolonged satiety Central nervous system effects: Acts on appetite centers in the brain to reduce hunger and food intake Protects pancreatic -cells: Promotes cell proliferation and inhibits apoptosis GLP-1 Receptor Agonists in Clinical Practice GLP-1 receptor agonists (GLP-1 RAs) are medications designed to mimic the action of endogenous GLP-1 but with enhanced pharmacokinetic properties

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18(2):185 Multifunctionality and possible medical application of the BPC 157 peptide: literature and patent review Bock-Marquette I, Maar K, Maar S, Lippai B, Faskerti G, Gallyas F Jr, Olson EN, Srivastava D., International Immunopharmacology , 2023

Ultimately, increasing the efficiency of the cancer immunotherapy and highlighting the potential of these nanocarriers as precise delivery agents, antigen-releasing agents, and aiding in dendritic cell activation