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These agents mimic the action of endogenous GLP-1, an incretin hormone released from intestinal L-cells in response to nutrient intake

10.1186/s12933-019-0916-z 58 FonsecaV.SchweizerA.AlbrechtD.BaronM

One study found patients regained about two-thirds of their weight loss within a year after stopping weekly semaglutide injections

10.1152/physiolgenomics.00193.2006 37

Others maintain regular use indefinitely with good results

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