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While the general principles of N-terminal acetylation and C-terminal amidation are well established in peptide chemistry, their specific effects on the AEDG sequences biological activity, pharmacokinetics in research models, and pathway engagement have not been formally evaluated in peer-reviewed literature (8)
DOI: 10.2174/1381612824666180712110447
Mammalian proapoptotic factor ChaC1 and its homologues function as glutamyl cyclotransferases acting specifically on glutathione
Deshwal, S
Basic Clin Pharmacol Toxicol 98:521522
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