J Pediatr Surg (2000) 35(6):84751.10.1053/jpsu.2000.6861 176 DruckerDJYustaBBousheyRPDeForestLBrubakerPL
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M., Castle, I
They found that for FDA approved GLP-1s for weight loss, liraglutide (Saxenda) and semaglutide (Wegovy), the percent of side effects reported was as follows: Nausea: 42.2% Diarrhea: 21.9% Vomiting: also 21.9% Constipation: 8.4% They report that although the incidence of side effects were similar among medications, semaglutide had the greatest risk of nausea, diarrhea, and vomiting, whereas liraglutide had the greatest risk of upper abdominal pain
Adequate hydration often helps
Unlike single-pathway GLP-1 receptor agonists, Mazdutide engages complementary mechanisms influencing appetite suppression and metabolic rate regulation