Potential insulin sensitivity changes While no direct evidence suggests a negative effect on blood sugar, some peptides may affect insulin signaling over time
But many other peptides promoted online have never been approved, making them technically illegal to market as drugs
That said, GI issues have many causes and BPC-157 is not a substitute for a proper diagnosis
Cardiovascular Events Patients with pre-existing heart conditions may be at higher risk of serious cardiovascular side effects if injections contain stimulants
Tendon and Ligament Repair Moderate to Strong Evidence Evidence Rating: Moderate-Strong (Several animal studies, some independent replication) Research support for musculoskeletal healing is substantial: Achilles tendon injuries Ligament damage (MCL, ACL) Rotator cuff healing General tendinopathy Surgical repair enhancement The FAK-paxillin mechanism and VEGF upregulation provide clear biological rationale for these effects
Regardless of mechanism, improved comfort often accompanies early protocol phases