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Acute high dose toxicity of TCs is characterized by diarrhea, vomiting, leukocytosis, haemorrhage, and circulatory shock and death, whereas chronic low dose toxicity is characterized by anorexia, reduced weight gain, neuroendocrine and immunologic changes [91, 94]
El glutatin se conoce como el antioxidante maestro
doi: 10.1073/pnas.1215840110 162 YingWTsengAChangRCWangHLinYLKanameniSet al
Yajima N, Wada R, Yamagishi S, Mizukami H, Itabashi C, Yagihashi S
In a 6 yr old leukemia patient receiving pentostatin 0.25 mg/kg daily for 3 successive days by direct iv injection, serum and CSF (via lumbar puncture) pentostatin concentrations 4 hr after the initial dose were approximately 147 and 19 ng/ml, respectively, using an enzyme-inhibition titration assay
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