Shanzhiside methylester, the principle effective iridoid glycoside from the analgesic herb Lamiophlomis rotata, reduces neuropathic pain by stimulating spinal microglial -endorphin expression
One of its main effects is slowing down melanin production the pigment that causes dark spots and uneven skin tone
Implications for Obesity Treatment Policy Tirzepatide appears to be a cost-effective option with favorable modeled clinical outcomes compared to semaglutide for managing obesity and overweight in the U.S
BMC Endocrine Disorders , 19 (1)
This targeted action results in gradual reduction of existing pigmentation while preventing the formation of new dark spots and uneven skin tone
Saugy M, Robinson N, Saudan C, Baume N, Avois L, Mangin P