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This sustained effect after discontinuation is consistent with the gene expression and epigenetic normalization model of action, where the peptide is thought to reset cellular regulatory programs rather than requiring continuous presence to maintain its effects

Description: BPC-157 is a synthetic pentadecapeptide with the amino acid sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val

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Endocrinol., 165(3):569-577, 2000

(PubMed) Rolo AP, Teodoro JS, Palmeira CM