Downregulation of SLC7A11 disrupts cysteine metabolism, leading to decreased intracellular cystine and GSH levels, impairing GPX4 activity and triggering lipid peroxide accumulation and ferroptosis (79,81,82)
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10.1038/s41392-021-00701-5 83 ZhangT.ChaboryE.BritanA.GrignardE.PitiotO.SaezF.et al (2008)
Your work in the lab has the potential to unlock new understandings of human biology, and our job is to provide the reliable, high-purity compounds you need to do that work
Key advantages of bacteriostatic water: Long shelf life after opening thanks to its bacteriostatic properties, the water can be safely used for many days or weeks after first opening (usually up to 28 days when refrigerated) Ability for multiple withdrawals you can withdraw water multiple times from the same vial without the risk of bacterial contamination Safety for reconstituted peptides peptides dissolved in bacteriostatic water can be safely stored for a longer time (usually 2-4 weeks in the refrigerator) Protection against contamination benzyl alcohol protects the solution from the growth of bacteria that might enter during withdrawal Sterile Water Single-use Sterile water for injection is pure, sterile water without any added preservatives
Alpha Lipoic Acid (ALA) ALA is a potent antioxidant that can regenerate other antioxidants, including glutathione