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[8] No serious systemic events attributable to topical GHK-Cu have been documented in the literature to date, yet comprehensive long-term surveillance data are still limited

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Indian J Exp Biol 2000;38:607-9

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Considering the temporal nature of hypovolemia following increased semaglutide dosage, improvement of the ischemic colitis on the second colonoscopy following drug discontinuation, and lack of signs of infection during the initial admission, semaglutide was still deemed the most likely culprit of the colonic ischemia