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Injection site reactions : Localised redness, swelling, or discomfort at the injection site

many times the total amount a patient would receive weekly from this injection

In the discussion around mounjaro or ozempic for weight loss , Tirzepatide may offer additional metabolic benefits because it targets two hormonal pathways instead of one

Liver Int 26(8): 1015-17 Wettergren A et al (1998): Glucagon-like peptide-1 inhibits gastropancreatic function by inhibiting central parasympathetic outflow

FDA.gov (accessed 26 July 2025)

The primary goals of the study were to assess the percentage change in body weight and the proportion of participants achieving at least a 5% reduction in body weight from baseline after 76 weeks of treatment