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There is no primary-source efficacy data supporting those human doses
If no blood is aspirated, then the medication can be pushed through slowly
(2010) 28:e13042
Vitamin B12 deficiency is a medical condition resulting from a lack of vitamin B12
High homocysteine could also mean you have an MTHFR gene mutation, which makes you less efficient at converting inactive folate to the active form of folate that breaks down homocysteine
This doesn't mean expensive always equals better, but it does suggest that formulation expertise matters for tolerability
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